MyBioSource.com's MOUSE ANTI HUMAN CD227 is a Mouse monoclonal antibody. The MOUSE ANTI HUMAN CD227 Antibody was generated using CA 15-3, CA15-3, CD227, KL-6, MAM6, MUC1, and Mucin 1 as the antigen. It reacts with Human. This antibody has been shown to work in applications such as: ELISA, Flow Cytometry, Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
Mouse anti Human CD227 antibody, clone C595 (NCRC48) recognizes CD227, also known as mucin 1 which is a breast cancer associated mucin encoded by the Muc-1 gene. Mucins are a family of high molecular weight, heavily glycosylated proteins (glycoconjugates) produced by many epithelial tissues in vertebrates. CD227 is expressed on most secretory epithelium, including mammary gland and some hematopoietic cells. This protein is overexpressed abundantly in >90% breast carcinomas and metastases. Mouse anti Human CD227 antibody, clone C595 recognizes the peptide epitope ARG-PRO-ALA-PRO within the protein core of the mucin